In 2006, Sylvain Lesné and seven coauthors published a paper on Alzheimer’s disease, “A specific amyloid-beta protein assembly in the brain impairs memory,” in Nature, the world’s most prestigious scientific journal. This was a major paper in the development of the “amyloid hypothesis,” a proposed mechanism for how Alzheimer’s disease afflicts its victims.
Related problem is that vast majority of publications are useless. The tiny fraction which are fraudulent becomes less tiny once you start filtering out uninteresting papers, the job, in essence, of peer review.
Paul Meehl fretted about this problem in the 1980s. 36 years later we are still debating
Related problem is that vast majority of publications are useless. The tiny fraction which are fraudulent becomes less tiny once you start filtering out uninteresting papers, the job, in essence, of peer review.
Paul Meehl fretted about this problem in the 1980s. 36 years later we are still debating
https://www.argmin.net/p/youre-gonna-run-when-you-find-out
Very interesting! Have you thought about how this might develop in the future with Large Language Models x replication crisis?